Translational Therapeutics Training at the Indiana University School of Medicine involves rigorous translational (both basic and clinical) training in research provided by no other specialty, that is designed to prepare fellows for positions as independent investigators in academia, industry and regulatory agencies. The training program is one of a few funded by the National Institutes of Health, certified by the American Board of Clinical Pharmacology, and has been the recipient of the Center of Excellence in Clinical Pharmacology grant from the Pharmaceutical Manufacturer's Foundation and is currently recognized by NIH as a Center of Excellence in Pediatric Pharmacology.
The program involves a series of didactic classes designed to provide basic skills in clinical trial design, pharmacokinetics and pharmacogenetics, biomarker assessment and development as well as ethical issues in clinical research. These classes take place within a rich research environment that involves the study of therapeutics in humans of all ages and ethnicities, at many levels. Fellows have a wide spectrum of research opportunities built around work in outstanding Clinical and Infomatics Centers at the Indiana University School of Medicine and with a vigorous group of well-funded faculty. Areas of particular research strength include the study of personalized medicine approaches to therapeutic effect and the influence of pharmacogenetics and pharmacokinetics on inter-individual response to drug therapy for cancer, HIV, cardiovascular and psychiatric disease in children and pregnant women as well as in adults.
The presence of strong groups of investigators in health services research in the Regenstrief Institute means that many of our studies can be carried all the way to real pharmacoeconomic and health care outcomes. Research experience in this area can include the use of large clinical databases to perform epidemiologic studies and the design and conduct of interventional trials in large populations of patients to address issues of cost effectiveness as applied to drugs.
The Indiana University School of Medicine has a strong Center for Bioethics that allows fellows the opportunity to experience excellent training in the ethical issues related to clinical research, and to understand their research in the context of national policy that affects research in clinical therapeutics.
Fellowship salaries are determined by the NIH Post-doctoral training scale. Trainees who qualify for the NIH-funded fellowship, i.e., are US citizens or permanent residents, will be eligible for $35,000 of loan reimbursement per year for two years via the NIH Clinical Research Loan Reimbursement program.
~ Indiana University welcomes applications from individuals from diverse populations that are under-represented in science or academic, including ethnic and racial minorities, disadvantaged backgrounds and with physical disabilities.
Submit an application
For further information, please contact:
Division of Clinical Pharmacology
Indiana University School of Medicine
950 West Walnut Street, Room 402
Research Institute II (R2)
Indianapolis, IN 46202