Dr. Flockhart came to Indiana University in the summer of 2001 as the Chief of the Division of Clinical Pharmacology. He came from Georgetown University Medical Center, where he served as the Francis Cabell Brown Chair and Chief of the Division of Clinical Pharmacology and Director of the Pharmacogenetics Core Laboratory. His research is focused on clinically-relevant applications of pharmacogenetics and drug interactions. He grew up in Edinburgh, Scotland and took Honors in Biochemistry at the University of Bristol, England. He subsequently obtained a PhD from the Welsh National School of Medicine, and an MD from the University of Miami School of Medicine. He performed a residency in Internal medicine at Georgetown University Medical Center, and after a year as Chief Medical Resident, completed a fellowship in Clinical Pharmacology in the Division of Clinical Pharmacology at Georgetown University Medical Center.

He served on the faculty of the Georgetown Division of Clinical Pharmacology from 1993 on, and as the Director of the Pharmacogenetics Core Laboratory beginning in 1995. He has been involved in the development of new pharmacogenetic tests using array, chip and other biotechnologies, and a focus of his research is to evaluate and communicate the value of pharmacogenetic tests to physicians and pharmacists involved in clinical practice. He is now the Principal Investigator of the Indiana University Medical Center site of the national Pharmacogenetics Research Network organized by the NIGMS. Dr. Flockhart has more than 100 publications in the area of pharmacology and clinical pharmacology, in which he specializes in the study of drug interactions and the contribution of genetics to inter-individual variations in drug response. He is a member of the American Board of Clinical Pharmacology and has served on the Executive Committee and Board of the American Society for Clinical Pharmacology and Experimental Therapeutics, and as Chair of the Government Affairs Committee. He is currently the Vice-Chair of the Pharmacokinetics and Drug Metabolism Section of ASCPT. Dr. Flockhart is an active teacher, and teaches the Clinical Pharmacogenetics portion of the annual course in Clinical Pharmacology at the National Institutes of Health, in Bethesda, MD and the Pharmacogenetics section of the Annual Review in Clinical Pharmacology provided by the ASCPT as well as the "Clinical Pharmacology Update" module at the Annual Meeting of the American College of Physicians and he coordinates the bi-annual review of Clinical Pharmacology conducted by the ASCPT.

His website www.drug-interactions.com, a tool to improve rational prescribing, has been cited by the Washington Manual of Medicine and Therapeutics, The Harriet Lane Handbook for Pediatrics and the Medical Letter, and receives approximately 20,000-25,000 visits per month from physicians and scientists and around the world.