Department of Medicine

Clinical Pharmacology

Friday Journal Club (2012)


Journal Club meets on Fridays from 9:00 a.m. - 10:00 a.m. in Conference Room (Room W7120) in Wishard Hospital, Myers Building, 7th Floor.

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Date Presenter Journal Title
6-Jan Robert Bies, Abdulateef Aregbe, Mohamed Ahmed, Brian Overholser Clin Pharmacol Ther. 2011 Dec;90(6):867-75. Assessing the Probability of Drug-Induced QTc-Interval Prolongation During Clinical Drug Development
13-Jan David Jones, Viplove Senadhi, Abdelhadi Ahmed, James Tisdale N Engl J Med. 2011 Dec 15;365(24):2268-76. Dronedarone in High-Risk Permanent Atrial Fibrillation
20-Jan David Flockhart, Eric Sherer, Noha Mourad, Rolf Kreutz Circ Cardiovasc Genet. 2011 Nov 18. A Large Candidate Gene Survey Identifies the KCNE1 D85N Polymorphism as a Possible Modulator of Drug-Induced Torsades de Pointes
27-Jan No Journal club    
3-Feb No Journal club    
10-Feb Ray Galinsky, Rebecca Lynch, Lateef Aregbe(L) N Engl J Med. 2011 Dec 29;365(26):2497-506. SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
17-Feb Claire Xu (L), Brian Overholser The Utility of Electronic Health Record in Clopidogrel PGx
CYP2C19 and Clopidogrel Response (commentaries)
Predicting Clopidogrel Response Using DNA Samples Linked to an Electronic Health Record
24-Feb Callaghan, Eileen, Ingrid (L) Journal of Antimicrobial Chemotherapy. 2011; 66: 2092-2098 Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens
2-Mar Jason Robarge, Eric Sherer, and Rich Bergstrom Sci Transl Med. 2012 Feb 22;4(122):122ra21. First-in-Human Testing of a Wirelessly Controlled Drug Delivery Microchip
9-Mar NO JC    
16-Mar ASCPT - NO JC     
23-Mar David Haas , Claire Li (L), Eric Benson Keelan antibiotics distribution in pregnant sheep
30-Mar 4th Year Course - NO JC     
6-Apr David Flockhart, Rebecca Lynch, David Thacker (L)

Drug target identification using side-effect similarity (Main)

Drug target identification using side-effect similarity (supplement)

13-Apr Desta , Heng Zhao (L), Heqiao Dai Differential Expression of the 18 kDa Translocator Protein (TSPO) by
20-Apr Lang Li, Claire Xu , Tonia Thompson (L) Data driven prediction of Drug interactions 2012
27-Apr Todd Skaar, Eileen Han (L), Jasper Stevens Randomized and Clinical Effectiveness Trial Comparing Two Pharmacogenetic Algorithms and Standard Care for Individualizing Warfarin Dosing: CoumaGen-II
4-May Rob Bies, Claire Li, Nieves Velez de Mendizabal (L) An Agonist–Antagonist Interaction Model for Prolactin Release Following Risperidone and Paliperidone Treatment
11-May David Jones , Santosh Philips (L), Jodi Skiles Pac Symp Biocomput. 2012:410-21. Discovery and explanation of drug-drug interactions via text mining
18-May Jamie Renbarger, Jason Robarge, Deshun Lu (L) Gemfibrozil is a Strong Inactivator of CYP2C8 in Very Small Multiple Doses
1-Jun Beth Pflug (L), Trou Quigg Association of Coffee Drinking with Total and Cause-Specific Mortality
8-Jun Sara Quinney, Lateef Aregbe PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo
3-Aug Sara Quinney, Tonia Thompson ,Jason Robarge (L) Non-Invasive Prenatal Measurement of the Fetal Genome
10-Aug Canceled    
17-Aug Canceled- Conflict of Interest Webinar    
24-Aug Todd Skaar, Nieves Velez de Mendizabal ,Claire Li (L) Identification of Drugs Using a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells
31-Aug No Journal Club    
7-Sep David Jones, Ingrid Metzger , Eileen Han (L) Mechanism of Efavirenz Influence on Mathadone
14-Sep Beth Pflug, Albany (L), Heqaio Expressed Pseudogenes in the Transcriptional Landscape of Human Cancers
21-Sep Rob Bies, Benson, Ferguson (L) Mouse to Man: Predictions of Human Pharmacokinetics of Orally Administered Docetaxel From Preclinical Studies
28-Sep Lang Li, Falah (L), Robarge   ** Cancelled **
5-Oct Tisdale, Thompson, Claire Xu (L) Azithromycin and the Risk of Cardiovascular Death
12-Oct Lang Li, Falah (L), Robarge Clinical Assessment Incorporating a Personal Genome
19-Oct Kreutz, Deshun Lu (L), Claire Li    
26-Oct Overholser, Ingrid, Heng (L)    
2-Nov Desta, Nieves (L), Eileeen Han    
9-Nov Thacker, Quigg, Heqaio (L)    
16-Nov Foster, Albany (L), Ferguson    
23-Nov Thanksgiving - No JC    
30-Nov Bergstrom, Benson, Robarge (L)    
7-Dec Decker, Falah, Claire Xu (L)    
14-Dec Flockhart, Smitha (L), Claire Li    
21-Dec Quinney, Thompson (L), Heng    
28-Dec Holiday - No JC